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一、基本信息
男,博士,副教授,中共党员,现任药学院副院长,硕士生导师。2015年6月毕业于重庆大学,获化学工程与技术专业工学博士学位。中国化学会会员、山东省生物医药学会理事。主持山东省自然科学基金青年项目1项、菏泽市社科联项目1项、菏泽学院科研基金3项,2020年获菏泽市自然学科学优秀学术成果奖一等奖。以第一作者或通讯作者在Chemical Engineering Journal、Talanta、Journal of Molecular Liquids、Dyes and Pigments等杂志上发表SCI论文20余篇、中文核心论文4篇、获批发明专利2件。指导学生获批“挑战杯”等十余项省部级以上学科竞赛奖励。
二、研究方向
小分子药物结构修饰、肿瘤靶向荧光探针设计、金属缓蚀等。
三、教授课程
《有机化学》、《化工原理》
四、主持的主要科研项目
1.瑞舒伐他汀钙侧链合成关键工艺研究(横向),60万元,负责人,2023.04-2025.04. (在研)
2.低能耗烟气二氧化碳相变吸收剂的研制,90万元,负责人,2023.01-2027.12. (在研)
3.消毒剂对金属和橡胶制品的缓蚀剂,15万元,负责人,2023.12-2024.06. (在研)
4.基于有机离子液体型分子自组装的金属缓蚀的研究,ZR2020QB180,山东省自然科学基金青年基金,10万元,负责人,2020.01-2023.12.(结题)
5.高新技术企业下高端污染调研及环境保护建议,菏泽市社科联项目,负责人,2020-2021.(结题)
五、近五年代表性研究成果
学术论文:
[1] C Shan, R R Li, X C Wang* Efficient construction of a b-naphthol library under continuous flow conditions, RSC Adv, 2024, 14, 2673-2677.
[2] Y T Shi, J L Xiong, H R Li, F Gao, X C Wang*, S T Zhang. Inspired dual functional adsorption films of armed molecules on copper. The Canadian Journal of Chemical Engineering, 2024, 102(2): 722-737.
[3] G Ding, X C Wang*, C X Ling-hu, Y J Fan, L L Zhou, D R Luo, S Q Meng, J P Meng, W Chen, Y Liu, G Y Gao, D Peng. AIE-active light up probe for sensitive detection of amine vapors and its practical application in food spoilage monitoring. Tetrahedron, 2023, 134: 133306.
[4] G Ding, X C Wang*, D R Luo, S Q Meng, L L Zhou, Y J Fan, C X Ling-hu, J P Meng, W T Si, Q Z Chen , R M Bi. A simple ESIPT combines AIE character “turn on” fluorescent probe for Hcy/Cys/GSH detection and cell imaging based on coumarin unit. Dyes and Pigments, 2023, 208: 110762.
[5] G Ding, X C Wang*, Y J Fan, C X Ling-hu, L L Zhou, S B Xie, J L Chen, Y F Zhang, G Y Gao. Biphenyl-based AIE-active turn-on fluorescent probes for simultaneous sensing of biothiols and amine vapors and visual real-time monitoring of seafood spoilage. Dyes and Pigments, 2023, 220: 111686.
[6] W P Luo, S T Zhang, X C Wang*, F Gao, H R Li. Ionic macromolecules based on non-halide counter anions for super prevention of copper corrosion, J Mol Liq, 2022, 349: 118156.
[7] S Mao, G Ding, K Wang, Q Wang, Y Gao, X Liang, D M Meng, J Wang, X C Wang*. A novel mitochondria-targeted triphenylamine-based fluorescent chemo-sensors for fast detection of H2O2 in living cells and its imaging application, J Mol Struct, 2022, 1270:133951.
[8] S Mao, G Ding, Q Wang, X T Liu, K Wang, Y Gao, X C Wang*, X Liang, D M Meng. A novel mitochondria-targeted fluorescent sensor for the HOCl/ClO- detection and imaging application in living cells, Tetrahedron, 2022, 123: 132983.
[9] Z Q Wang, X C Wang*, S T Zhang, Z Y Wang, F Gao, H R Li. Simple and prompt protonation of new dyes containing double conjugated imine bonds to strengthen the protection of copper in aggressive sulfuric acid solution, J Mol Liq, 2021, 341:117402.
[10] G Ding, X C Wang*, W H Zhao, S Mao, J Wang, S T Kang, J P Meng, H P Liu, H S Yang, S T Liang. A portable AIEgen-based organic fluorescence sensor design and its reusable application in information storage and pH detection, Tetrahedron, 2021, 92 :132258.
[11] H J Huang, Y Fu, F H Li, Z Q Wang, S T Zhang, X C Wang*, Z Y Wang, H R Li, F Gao. Orderly self-assembly of new ionic copolymers for efficiently protecting copper in aggressive sulfuric acid solution, Chem. Eng.J, 2020, 384:123293.
[12] Y K Duan, G Ding, M Y Yao, Q Wang, H Guo, X C Wang*, Y F Zhang, J Y Li, X J Li, X Z Qin. Novel triphenylamine-based fluorescent chemo-sensors for fast detection of thiophenols in vitro and in vivo, Spectrochim Acta A, 2020, 236:118348.
[13] X C Wang*, G Ding, Y K Duan, Y J Zhu, G S Zhu, M Wang, X J Li, Y F Zhang, X Z Qin. A novel triphenylamine-based bis-Schiff bases fluorophores with AIE-Activity as the hydrazine fluorescence turn-off probes and cell imaging in live cells, Talanta, 2020, 217:121029.
[14] X C Wang*, G Ding, Y K Duan, M Wang, G S Zhu, X J Li, Y F Zhang, X Z Qin. Novel ‘naked-eye’ Bis-Schiff base fluorescent chemosensors for sensitive detection of Zn2+ and bio-imaging in living cells, Tetrahedron, 2020, 76:131108.
[15] X C Wang*, G Ding, Y X Wang, S Mao, K Wang, Z D Ge, Y F Zhang, X J Li, C H Hung. Novel application of a fluorescent dye based on triphenylamine: Rapid detection of hydrazine in living cells and in vitro, Tetrahedron, 2020, 76:131726.
[16] H J Huang, Y Fu, X C Wang, Y C Gao, Z Q Wang, S T Zhang, H R Li, F Gao, L Y Chen. Nano- to Micro-Self-Aggregates of New Bisimidazole-Based Copoly(ionic liquid)s for Protecting Copper in Aqueous Sulfuric Acid Solution, ACS Appl. Mater. Interfaces, 2019, 11:10135-10145.
[17] G Ding, X C Wang*, X J Li, H P Liu, L X Wang, N Liu, F Gao, Z Q Wang. Nano-aggregates of furan-2-carbohydrazide derivatives displaying enhanced emission with a bathochromic shift, RSC Adv, 2019, 9:36097.
[18] 毛申,彭云佩,刘聪聪,刘瑶,王琦,梁笑,王新潮*.基于不同荧光发色基团的锌离子荧光探针的研究进展. 理化检验-化学分册,2024,60(4),433-439
[19] 李秀娟,刘瑶,彭云佩,刘聪聪,刘嘉宁,谢东,王新潮*.用于次氯酸/次氯酸根(HClO/ClO- )检测的荧光探针. 化学研究与应用,2023,35(12):2946-2951
[20] 张晓辉, 王璇, 杨娜, 毛申, 梁笑, 王新潮*, 李秀娟, 刘凤谨.一种新型快速检测半胱氨酸的荧光探针.分析试验室, 2022,41(01):55-58.
[21]一种超支化有机离子液体型金属缓蚀剂及其制备方法[P].中国专利.CN114164431B.2024.02.20
[22]一种三苯胺衍生物希夫碱类有机荧光探针及其制备方法[P].CN109970600B, 2021-11-02.