化学反应工程实验室坐落于综合实验楼E419，是药学院的专业实验室。实验室面积为123.66平方米，实验室负责人为梁笑博士。实验室现用于教学实验室，负责药学院师生的日常实验教学等工作。主要的实验设备有荧光分光光度计、紫外可见分光光度计、电化学工作站、旋转蒸发仪、微波化学反应器、数显熔点测试仪等；主要讲授的课程有《有机化学》、《物理化学》、《药物化学》、《天然药物化学》、《化工制图与AutoCAD》、《药物合成反应》、《制药工艺学》等。众多学子在本实验室从事学习、科研活动，曾获得第七届山东省大学生医药生物技术技能大赛三等奖、“科巢杯”第九届山东省大学生医药生物技术技能大赛一等奖、三等奖等。
本实验室发表过的主要文章有：
[1] Shen Mao, Ge Ding, Kai Wang, Qi Wang, Yue Gao, Xiao Liang, Dongmei Meng, Juan Wang, Xinchao Wang. A mitochondria-targeted dual-reactable fluorescent probe for fast detection of H2S in living cells[J]. Journal of Molecular Structure, 2022, 1270: 133951.
[2] Shen Mao, Ge Ding, Qi Wang, Xiaotong Liu, Kai Wang, Yue Gao, Xinchao Wang, Xiao Liang, Dongmei Meng. A novel mitochondria-targeted fluorescent sensor for the HOCl /ClO− detection and imaging application in living cells[J]. Tetrahedron, 2022, 123, 132983.
[3] Dan Qiao, Landie Li, Tangliang Shen, Jiejie Yang, Hao Chang, Xiao Liang, Lu Zhang, Qianqian Wang, Ning Liu, Wei Zhao, and Luqing Shang*, Establishment of a Customizable Fluorescent Probe Platform for the Organelle-Targeted Bioactive Species Detection[J]. ACS Sens. 2020, 5, 7, 2247-2254.
[4] Xiao Liang, Lu Zhang, Bing Shi, Hao Chang, Dan Qiao, Tangliang Shen, Wei Zhao, Zheng Yin, Luqing Shang. Design and application of near-infrared fluorophore based on a novel thiazolidinedione - functionalized dicyanoisophorone. Talanta, 2020, 220, 121433.
[5] Zhiwei Deng, Xiufang Li, Hui Liu, et al., A nanoprobe for ratiometric imaging of glutathione in living cells based on the use of a nanocomposite prepared from dual-emission carbon dots and manganese dioxide nanosheets [J], Microchimica Acta, 2020, 187, 537.
Junye Li, Tingting Zheng, Hongjian Sun, Wengang Xu, Xiaoyan Li. Selective C–F/C–H bond activation of fluoroarenes by cobalt complex supported with phosphine ligands[J]. Dalton Transactions, 2013, 42(16): 5740-5748.
[6] Junye Li, Xiaoyan Li, Hongjian Sun. Synthesis and characterization of novel organonickel and organocobalt complexes via carbon–chlorine bond activation[J]. Journal of Organometallic Chemistry, 2013, 743: 114-122.
[7] Junye Li, Tingting Zheng, Hongjian Sun, Xiaoyan Li. Selectively catalytic hydrodefluorination of perfluoroarenes by Co (PMe 3) 4 with sodium formate as reducing agent and mechanism study[J]. Dalton Transactions, 2013, 42(36): 13048-13053.
[8] Junye Li, Xiaoyan Li, Lin Wang, Qingping Hu and Hongjian Sun. C–Cl bond activation and catalytic hydrodechlorination of hexachlorobenzene by cobalt and nickel complexes with sodium formate as a reducing agent. Dalton Trans. 2014, 43, 6660-6666.
[9] Junye Li, Hongjian Sun. Synthesis Structure and Properities of a Novel Nickel (Ⅱ)Choride Complex Supported by Phosphine Ligands Chinese Journal of Structural Chemistry 2015, 34(11) 1735-1741.
[10] Faguan Lu, Junye Li, Hongjian Sun, Xiaoyan Li. Selective C–H bond activation of 1, 2, 4, 5-tetrafluorobenzene by Co (PMe 3) 4[J]. Inorganica Chimica Acta, 2014, 416: 222-225.
[11] Tingting Zheng, Junye Li, Shumiao Zhang, Hongjian Sun, Xiaoyan Li. Selective C–F and C–H Activation of Fluoroarenes by Fe (PMe3) 4 and Catalytic Performance of Iron Hydride in Hydrosilylation of Carbonyl Compounds[J]. Organometallics, 2016, 35(20): 3538-3545.
