化学反应工程实验室坐落于综合实验楼E415，是药学院的科专业实验室。实验室面积为50平方米，实验室负责人为梁笑博士。实验室现用于科研实验室。主要的实验设备有多功能酶标仪（五功能）、旋转蒸发仪、低温冷却循环泵、循环水式多用真空泵、玻璃烘干器、恒温磁力搅拌器、数控超声波清洗器、分析天平、暗箱式紫外分析仪等；众多学子在本实验室从事学习、科研活动，曾获得省自然科学基金一项、菏泽学院博士基金一项、“科巢杯”第九届山东省大学生医药生物技术技能大赛三等奖等。
本实验室发表过的文章有：
[1] Xiao Liang, Lu Zhang, Bing Shi, Hao Chang, Dan Qiao, Tangliang Shen, Wei Zhao, Zheng Yin, Luqing Shang. Design and application of near-infrared fluorophore based on a novel thiazolidinedione - functionalized dicyanoisophorone. Talanta, 2020, 220, 121433.
[2] Xiao Liang, Xiaoyi Xu, Dan Qiao, Zheng Yin, Luqing Shang*. Dual Mechanism of an Intramolecular Charge Transfer (ICT)-FRET-Based Fluorescent Probe for the Selective Detection of Hydrogen Peroxide.[J]. Chemistry-an Asian journal,2017,12:3187-3194.
[3] Xiao Liang, Lu Zhang, Xiaoyi Xu, Dan Qiao Tangliang Shen, Zheng Yin,. Luqing Shang*. An ICT-Based Mitochondria-Targeted Fluorescent Probe for Hydrogen Peroxide with a Large Turn-On Fluorescence Signal[J]. ChemistrySelect,2019,4(4):1330-1336.
[4] Zhiqiang Han, Xiao Liang, Xuejiao Ren, Luqing Shang*, Zheng Yin*. A 3,7- Dihydroxyphenoxazine-based Fluorescent Probe for Selective Detection of Intracellular Hydrogen Peroxide[J]. Chemistry-An Asian Journal, 2016,11(6): 818-822.
[5] Zhiqiang Han, Xiao Liang, Yaxin Wang, Jie Qing, Lin Cao, Luqing Shang*, Zheng Yin*. The discovery of indole derivatives as novel hepatitis C virus inhibitors[J]. European Journal of Medicinal Chemistry, 2016, 116, 147-155.
[6] Dan Qiao, Tangliang Shen, Mengyuan Zhu, Xiao Liang, Lu Zhang, Zheng Yin, Binghe Wang*, Luqing Shang*. A highly selective and sensitive fluorescent probe for simultaneously distinguishing and sequentially detecting H2S and various thiol species in solution and in live cells.[J]. Chemical communications, 2018,54 (94): 13252-13255.
[7] Shen Mao, Ge Ding, Kai Wang, Qi Wang, Yue Gao, Xiao Liang, Dongmei Meng, Juan Wang, Xinchao Wang. A mitochondria-targeted dual-reactable fluorescent probe for fast detection of H2S in living cells[J]. Journal of Molecular Structure, 2022, 1270: 133951.
[8] Shen Mao, Ge Ding, Qi Wang, Xiaotong Liu, Kai Wang, Yue Gao, Xinchao Wang, Xiao Liang*, Dongmei Meng. A novel mitochondria-targeted fluorescent sensor for the HOCl /ClO− detection and imaging application in living cells[J]. Tetrahedron, 2022, 123, 132983.
[9] Dan Qiao, Landie Li, Tangliang Shen, Jiejie Yang, Hao Chang, Xiao Liang, Lu Zhang, Qianqian Wang, Ning Liu, Wei Zhao, and Luqing Shang*, Establishment of a Customizable Fluorescent Probe Platform for the Organelle-Targeted Bioactive Species Detection[J]. ACS Sens. 2020, 5, 7, 2247-2254.
